Ciprofloxacin Chloro Analog Impurity - Names and Identifiers
Ciprofloxacin Chloro Analog Impurity - Physico-chemical Properties
Molecular Formula | C17H18ClN3O3
|
Molar Mass | 347.8 |
Density | 1.483±0.06 g/cm3(Predicted) |
Boling Point | 612.0±55.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Appearance | Solid |
Color | Off-White to Beige |
pKa | 6.44±0.41(Predicted) |
Storage Condition | Refrigerator |
Ciprofloxacin Chloro Analog Impurity - Introduction
6-chloro-6-defloro Ciprofloxacin, also known as 6-chloro-6-defluciprofloxacin, is a structurally related impurity of Ciprofloxacin. The following is a description of the nature, use, preparation and safety information of the impurity:
1. Nature:
-Appearance: Colorless or yellowish solid.
-Molecular formula: C17H16ClFN3O3.
-Molecular weight: 367.8g/mol.
-Melting point:>200°C.
-Solubility: Almost insoluble in water, soluble in some organic solvents.
2. Use:
6-choro-6-defluoro Ciprofloxacin is mainly used for the preparation and analysis of reference substances in analytical chemistry, pharmaceutical industry or research. It is used as a reference substance for impurities in ciprofloxacin drug substance and to help determine the quality and purity of ciprofloxacin products.
3. Preparation method:
6-choro-6-defluoro Ciprofloxacin can be synthesized by synthetic chemical methods. A common synthetic method is to react the corresponding compound with an appropriate reagent and obtain the target product through a series of reaction steps.
4. Safety Information:
6-choro-6-defluoro Ciprofloxacin has limited safety data, so it should be operated in accordance with general laboratory safety practices. Contact with skin, eyes or inhalation of the substance may cause irritation or irritation. When using and handling 6-choro-6-defluoro Ciprofloxacin, be sure to take appropriate personal protective measures, such as wearing gloves, glasses and protective face masks.
Last Update:2024-04-10 22:29:15